《英文msh詞典》Late Onset Alzheimer Disease
[入口詞] Late Onset Alzheimer Disease
[主題詞] Alzheimer Disease
[英文釋義] A degenerative disease of the brain characterized by the insidious onset of dementia. Impairment of memory,judgement,attention span,and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60,and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al.,Principles of Neurology,6th ed,pp1049-57)